Aztreonam Lysine for Inhalation
Aztreonam lysine for inhalation is an antibiotic currently being studied in Phase III clinical trials for people with cystic fibrosis (CF) who have the bacteria (germ) Pseudomonas aeruginosa in their lungs. The currently available form of aztreonam is given by an injection, either into a vein (IV) or into a muscle, to fight infections.
Inhaled vs injected
The inhaled form of aztreonam is different from the injected form in that it has been specifically formulated with different ingredients for inhalation. It is important to study a new formulation to see whether it is safe and effective.
About inhaled antibiotics
Aztreonam lysine for inhalation is administered (taken) via the investigational (experimental) eFlow® Electronic Nebulizer. Inhaling an antibiotic using a nebulizer delivers the drug directly to the site of infection where it can fight the bacteria. Side effects for inhaled antibiotics are similar to other antibiotics and inhaled medications. These side effects may include allergic reaction, cough, shortness of breath, wheezing, chest tightness, headache, dizziness or nausea. The informed consent form will include a full list of the possible side effects.
Next: Learn about the eFlow® Electronic Nebulizer